29 April 4, Models, suppressors, and mechanisms of the disease. (Papers Due) Papers we are reading for today are: Flies?  What do flies have to do with a human disease? Kevin and Alix will walk us through all the back flips of how they did this screen. If you are curious about P elements and what they do. Check out the following Worse still: Baker's Yeast?  How can yeast help us understand Huntington's, or does it?  Your call. Jared and Tim will dazzle us with their footwork. Expect fire works.  Everyone pick your favorite gene and be prepared to ask them about the function! here is the supplemental material for the yeast paper, this is a good read because it actually tells you how they did this stuff. Here is the link to the Genome Deletion Project, which is the resource that they used to do this screen http://www-sequence.stanford.edu/group/yeast_deletion_project/deletions3.html Here is another paper that might be interested, but is not required reading for thursday Protein degredation and SUMO wrestling.