46 A review of strategies & tools, BACs, YACs & plasmids Today will be about strategies.  Thom will talk about the technologies and words involved in the cloning and characterization of the Huntington's disease gene.   http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=143100 A hands on BAC protocol from the folks at the Gensat project.  This gives you a feeling for what it is like to work with BACs and make BAC transgenic mice. Here is a very nice review on recombineering from the Copeland lab.   This is where you go to buy your handy dandy BAC http://bacpac.chori.org/ A short review on what a BAC is: